DESCRIPTION Gene Name Synonym CD7, GP40, TP41, LEU-9, Tp40 Species Human Accession P09564 Source HEK293 cells SPECIFICATIONS Amino acid sequence Ala26-Pro180 is expressed with a 10×His tag at the C terminus Molecular Weight 18 kDa（The protein migrates as 22~30 kDa under reducing condition (SDS-PAGE) due to glycosylation） Purity >95.0% as determined by SDS-PAGE Endotoxin <5 EU mg -1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND CD7 is a single-domain Ig superfamily molecule.CD7 is a transmembrane protein that is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development. CD7 is a cell surface costimulatory molecule expressed on T and NK cells. CD7 is highly expressed on malignant immature T cells and is generally absent on malignant mature T cells. Data SDS-PAGE Bioactivity Recombinant Human CD7 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 30-42 kDa. Measured by its binding ability in a functional ELISA. Immobilized human SECTM1 at 2 μg/ml (100 μl /well) can bind biotinylated human CD7-His with a linear range of 0.024-0.178 μg/mL. 仅供科研用途，不可用于临床诊断！