Product Information Description H3 Mouse polyclonal Protein full name Histone H3.1/Histone H3.2/Histone H3.3 Synonyms HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/ Immunogen Recombinant protein corresponding to Mouse H3 Isotype IgG Purity Affinity purification Predicted MW. 15 kDa Observed MW. 15 kDa Uniprot ID Q9Y5N1 Applications Applications Species Dilution Positive Tissue WB Human, Mouse, Rat, Yeast 1: 2000-1: 5000 brain, skeletal muscle, liver Background Histone-H3, histone cluster 2, H3a is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone-H3 is expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Images Storage Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE: 1.This product is intended for research only. 2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （ G2025 ）.