产品信息

蛋白质全称	热休克同源71kDa蛋白
别名	Heat shock 70 kDa protein 8, Hspa8, Hsc70, Hsc73, Constitutive heat shock protein 70, HSPA10, LAP1, NIP71, N-myristoyltransferase inhibitor protein 71, Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1, HSPA10, HSPA8
Uniprot ID	P63017
免疫原	KLH偶联的小鼠Hsc70合成肽
抗体亚型	IgG
预测分子量./观测分子量.	71 kDa / 71 kDa
纯化方式	亲和纯化

---

应用

应用	物种	稀释	阳性样品
WB 免疫印迹	小鼠, 大鼠	1: 100-1: 500	心, 肺, 脑

---

背景

HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease.

---

图像

WB检测Hsc70蛋白(货号 GB111799). 样品: 经RIPA裂解液(货号G2002)处理的蛋白质. 封闭: 封闭: 3%脱脂牛奶(货号GC310001)溶于TBST溶液, 室温孵育1小时. —抗: 1: 1000稀释, 4℃ 孵育过夜. 二抗: HRP标记山羊抗兔IgG (H+L) (货号GB23303), 1: 5000稀释, 室温孵育1小时.

---

储存

储存条件	在-20℃下储存一年, 避免反复冻融.
储存缓冲液	含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

---

注意:

1.本产品仅供研究使用.

2.建议用一抗稀释液(G2025)稀释本产品.