DESCRIPTION Synonym IL7,Interleukin-7 Species Mouse A ccession P10168 Source HEK293 cells SPECIFICATIONS Amino acid sequence Met1-Ile154 is expressed with a 10×His tag at the C terminus Molecular Weight 17.8 kDa Purity >95.0% as determined by SDS-PAGE Endotoxin <5 EU·mg -1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Interleukin-7 (IL-7) was discovered in 1980s. It is one of the members of IL-2 superfamily. IL-7 is a cytokine that has been known since long in immunology, mainly regarding its effects on T-cells and B-cells. IL-7 has been demonstrated to be necessary for both B-cell and T-cell proliferation and lack of IL-7 causes immature immune cell arrest. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL-7 plays in aging may permit parsimonious preventative or therapeutic solutions for diverse conditions. Data SDS-PAGE Bioactivity Testing in progress Active Recombinant Mouse IL-7 Protein was determined by SDS-PAGE with Coomassie Blue. 仅供科研用途，不可用于临床诊断！