Product Information Protein full name Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) (Transcription factor ERGB) Gene Id 2313 Immunogen Synthesized peptide derived from human FLI1 Uniprot ID Q01543 Source Mouse/IgG1, Kappa Concentration 1 mg/ml Purity The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. Applications IHC/IF Human 1: 200-1: 500 hemangioendothelioma Background Friend leukemia virus integration1 (FLI1) that is also termed EWSR2 encodes a sequence-specific transcriptional activator involved in Ewing’s sarcoma (EWS), a malignant small, round, blue cell tumour. It is a rare disease in which cancer cells are found in the bone or in soft tissue. The most common areas in which it occurs are the pelvis, the femur, the humerus, the ribs and clavicle. And EWS occurs most frequently in teenagers and young adults. FLI1 protein may act as an aberrant transcription factor, but exact mechanisms of oncogenesis remains unknown. Images Immunohistochemistry analysis of paraffin embedded human hemangioendothelioma using FLI1 (GB14084) at dilution of 1: 200 Storage Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. NOTE: 1.This product is intended for research only. 2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （ G2025 ）.