Recombinant Anti-MyD88 antibody (Rabbit mAb)
- 50 μL
产品信息
蛋白质全称 | 髓样分化初级反应蛋白MyD88 |
别名 | MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88) |
Uniprot ID | Q6Y1S1 |
免疫原 | 大鼠MyD88重组蛋白 |
抗体亚型 | IgG |
克隆号 | SB557 |
预测分子量./观测分子量. | 33 kDa / 33 kDa |
纯化方式 | 亲和纯化 |
应用
| 应用 | 物种 | 稀释 | 阳性样品 |
| WB 免疫印迹 | 人, 小鼠, 大鼠 | 1: 1000-1: 2000 | Raji细胞, NIH3T3细胞, PC-3细胞 |
背景
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.
图像
| WB检测MyD88蛋白(货号 YB15280). 样品: 经RIPA裂解液(货号Y2013)处理的蛋白质. 封闭: 3%脱脂牛奶(货号YC310012)溶于TBST溶液, 室温孵育1小时. —抗: 1: 1000稀释, 4℃ 孵育过夜. 二抗: HRP标记山羊抗兔IgG (H+L) (货号YB23314), 1: 5000稀释, 室温孵育1小时. |
储存
| 储存条件 | 在-20℃下储存一年, 避免反复冻融. |
| 储存缓冲液 | 含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液. |
注意:
1.本产品仅供研究使用.
2.建议用一抗稀释液(Y2036)稀释本产品.
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