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Anti-PD-L1 Rabbit pAb

¥1650
货号:YB11350
品牌:YIKE
规格:
  • 100 μL
数量:

Product Information



Description PD-L1 rabbit polyclonal
Protein full name Programmed cell death 1 ligand 1

Synonyms

CD274, B7-H, B7H1, PDL-1, PDCD1L1, PDCD1LG1, PDL1, CD274 molecule, Programmed cell death 1 ligand 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PD-L1

Isotype IgG
Purity Affinity purification

Predicted MW.

33 kDa

Observed MW.

50 kDa

Subcellular location

Cell membrane

Uniprot ID Q9EP73




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 600-1: 800

liver,muscle,lung,heart

IHC

Human

1: 500-1: 1000

lung

IF

Human

1: 500-1: 1000

lung




Background



Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

   



Images



image.png

Western blot analysis of PD-L1 (GB11339) at dilution of 1:800.

Lane 1:Human liver cancer tissue lysate

Lane 2:HepG2 cell lysate

Lane 3:Mouse muscle tissue lysate

Lane 4:Mouse lung tissue lysate

Lane 5:Mouse heart tissue lysate

Lane 6:Rat muscle tissue lysate

Lane 7:Rat heart tissue lysate



image.png

Immunohistochemistry analysis of paraffin-embedded human lung cancer using PD-L1 (GB11339) at dilution of 1:500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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