Product Information

Gene Name	TG
Protein Name	Thyroglobulin (Tg)
Human Gene Id	7038
Human Swiss Prot No	P01266
Immunogen	Synthesized peptide derived from human Thyroglobulin
Specificity	This antibody detects endogenous levels of human Thyroglobulin
Source	Mouse/IgG1, Kappa
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

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Applications

Applications	Species	Dilution
IHC、IF	Human	1:200-1:500

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Background

thyroglobulin(TG) Homo sapiens Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009],

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Images

	Immunohistochemical analysis of paraffin-embedded Follicular thyroid carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.
	Immunohistochemical analysis of paraffin-embedded Follicular thyroid carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.

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Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.