MDR/P-GP
￥0
货号：YB13568
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | MDR1/P Glycoprotein rabbit polyclonal |
| Protein full name | MDR1/P Glycoprotein |
| Synonyms | ABC20, ABCB1, ATP binding cassette, sub family B (MDR/TAP), member 1, ATP-binding cassette sub-family B member 1, CD243, CLCS, Colchicin sensitivity, Doxorubicin resistance, GP170 |
| Immunogen | KLH conjugated synthetic peptide derived from human MDR1:1051-1280/1280 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 141 kDa |
| Observed MW. | 141 kDa |
| Uniprot ID | P08183 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | liver, kidney, small intestine, brain |
Background
ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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