CYP7A1
- 50 μL
Product Information
| Description | CYP7A1 rabbit polyclonal |
| Protein full name | CYP7A1 |
| Synonyms | cholesterol 7 alpha-monooxygenase, Cholesterol 7-alpha-hydroxylase, Cholesterol 7-alpha-monooxygenase, CP7A, CYP 7, CYP7, CYPVII, Cytochrome P450 7A1, cytochrome P450, family 7, subfamily A, polypeptide 1, Cytochrome P450, subfamily VIIA (cholesterol 7 alpha monooxygenase) |
| Immunogen | KLH conjugated synthetic peptide derived from human CYP7A1:321-421/504 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 58 kDa |
| Observed MW. | 55 kDa |
| Uniprot ID | P22680 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | liver |
Background
CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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