PD-L1
￥0
货号：YB13448
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | PDL1 mouse monoclonall |
| Protein full name | Anti-PD-L1 antibody |
| Synonyms | B7 H, CD274, MGC142294, PD1L1 |
| Immunogen | Recombinant fragment corresponding to Human PD-L1 aa 39-191. Database link |
| Isotype | IgG |
| Purity | Protein A/G purified |
| Subcellular location | Cell membrane and Endomembrane system. |
| Uniprot ID | Q9NZQ7 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 100-1: 200 | lung SCC, cervical carcinoma, breast carcinoma |
Background
Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443, PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).
Images
Storage
| Storage | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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