Anti-Fas Rabbit pAb
- 50 μL
Product Information
| Description |
Fas rabbit polyclonal |
| Protein full name |
Tumor necrosis factor receptor superfamily member 6 |
|
Synonyms |
FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to human FAS |
| Isotype | IgG |
| Purity | Affinity purification |
|
Predicted MW. |
38 kDa |
|
Observed MW. |
38 kDa |
| Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1:500-1:1000 | kidney |
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Images
 |
All lanes are rat kidney tissue lysate Western blot analysis of FAS (GB13089) at dilution of 1:1000. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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