
Anti-Cytokeratin 10 Mouse mAb
- 50 μL
Product Information
Protein full name | Keratin, type I cytoskeletal 10 |
Gene Id | 3858 |
Immunogen | Synthesized peptide derived from human CK-10 |
Uniprot ID | P13645 |
Source | Mouse/IgG3, Kappa |
Concentration | 1 mg/ml |
Purity | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
IHC/IF | Human | 1: 200-1: 500 | cutaneous squamous cell carcinomas |
Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. As a type I keratin, keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia.
Images
|
Immunohistochemistry analysis of paraffin embedded human cutaneous squamous cell carcinomas using Cytokeratin 10 (GB14051) at dilution of 1: 200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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