产品信息

蛋白质全称	C型凝集素结构域家族2成员D
别名	CLAX, CLEC2D, Lectin like NK cell receptor, Lectin like transcript 1, LLT1, LLT-1, Clec2d5, C type lectin related f, OCIL, Osteoclast inhibitory lectin
Uniprot ID	Q91V08
免疫原	小鼠CLEC2D重组蛋白
抗体亚型	IgG
预测分子量./观测分子量.	24 kDa / 24 kDa
纯化方式	亲和纯化

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应用

应用	物种	稀释	阳性样品
WB 免疫印迹	大鼠	1: 500-1: 1000	脾, 胸腺

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背景

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts . Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs . CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and that their interaction differentially regulates NK- and T-cell functions . It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells.

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图像

WB检测CLEC2D蛋白(货号 GB113251). 样品: 经RIPA裂解液(货号G2002)处理的蛋白质. 封闭: 封闭: 3%脱脂牛奶(货号GC310001)溶于TBST溶液, 室温孵育1小时. —抗: 1: 1000稀释, 4℃ 孵育过夜. 二抗: HRP标记山羊抗兔IgG (H+L) (货号GB23303), 1: 5000稀释, 室温孵育1小时.

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储存

储存条件	在-20℃下储存一年, 避免反复冻融.
储存缓冲液	含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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注意:

1.本产品仅供研究使用.

2.建议用一抗稀释液(G2025)稀释本产品.