runx3
- 50 μL
Product Information
| Description | RUNX3 rabbit polyclonal |
| Protein full name | Runt-related transcription factor 3 |
| Synonyms | Runt-related transcription factor 3, Core-binding factor, Acute myeloid leukemia 2 protein, OncogeneAML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEBP2-alpha C |
| Immunogen | KLH conjugated synthetic peptide derived from human Runx3:151-250/415 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 44 kDa |
| Observed MW. | 43-48 kDa |
| Uniprot ID | Q13761 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 1000 | SW620, Hela |
Background
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|
| 货号 | 名称 | 规格 | 价格 | 操作 |
|---|