OPG
￥0
货号：YB13564
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | OPN rabbit polyclonal |
| Protein full name | OPN |
| Synonyms | MGC29565; OCIF; OPG; Osteoclastogenesis Inhibitory Factor; TNFRSF 11B; TNFRSF11B; TR 1; TR1; Tumor Necrosis Factor Receptor Superfamily Member 11b |
| Immunogen | KLH conjugated synthetic peptide derived from human OPG:221-300/401 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 43 kDa |
| Observed MW. | 43 kDa |
| Uniprot ID | O00300 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | heart , kidney, liver, Raji, placenta, stomach |
Background
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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