Product Information Description CXCR4 rabbit polyclonal Protein full name chemokine (C-X-C motif) receptor 4 Synonyms CD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM Immunogen CXCR4 fusion protein Ag1528 Isotype IgG Purity Affinity purification Predicted MW. 40 kDa Observed MW. 60-70 kDa Uniprot ID P61073 Applications Applications Species Dilution Positive Tissue WB Human, Mouse, Rat 1: 500-1: 2000 spleen Background C-X-C chemokine receptor type 4 (CXCR4) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription . CXCR4 also functions as a coreceptor for HIV-1 entry . Images Storage Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE: 1.This product is intended for research only. 2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （ G2025 ）.