Product Information Description AMPK alpha 1 rabbit polyclonal Protein full name 5'-AMP-activated protein kinase catalytic subunit alpha-1 Synonyms AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1 , PRKAA1 , AMPK1 Immunogen KLH conjugated synthetic peptide derived from human AMPK alpha 1:351-450/559 Isotype IgG Purity Affinity purification Subcellular location Cytoplasm , Nucleus Predicted MW. 64 kDa Observed MW. 64 kDa Uniprot ID Q13131, Q5EG47 , P54645 Applications Applications Species Dilution Positive Tissue WB Human, Mouse, Rat 1: 200-1: 1000 HepG2, HeLa IHC-P/IHC-F Human, Mouse, Rat 1: 100-1: 500 colon carcinoma, brain Background The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Images Storage Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE: 1.This product is intended for research only. 2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （ G2025 ）.