广州一科生物

全国400热线：400-8252586

购物车个人中心

实验类型

Recombinant Mouse PDL1(CD274) Protein (His-tag)

￥3960

货号：YB300613-M-100μg

品牌：YIKE

规格：

100 μg

数量：

DESCRIPTION
Gene Name Synonym	PDL1, CD274, B7H1, PDCD1L1, PDCD1LG1
Species	Mouse
Accession	Q9EP73
Source	HEK293 cells
SPECIFICATIONS
Amino acid sequence	Phe19-Thr239 is expressed with a 10×His tag at the N terminus
Molecular Weight	26.2 kDa
Purity	>95.0% as determined by SDS-PAGE
Endotoxin	<5 EU mg^-1
Formulation	Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization.
Reconstitution	Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation.
STORAGE
Stability and Storage	12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
BACKGROUND
PD-L1, which we first identified as a homologue of B7 family molecules, is expressed on immune cells, i.e., dendritic cells (DCs) and B and T cells, and controls T-cell immune responses such as peripheral tolerance, termination of immune responses and immune exhaustion after prolonged exposure to an antigen stimulus. PD-L1 plays a crucial role in the disease progression of multiple myeloma. PD-L1 has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 can bind to PD-1 expressed on cytotoxic T lymphocytes (CTLs), resulting in the escape from immune surveillance by the induction of CTL apoptosis. PD-L1 is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
Data
SDS-PAGE		Bioactivity
		Testing in progress.
Recombinant Mouse PDL1 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 35-50 kDa.

仅供科研用途，不可用于临床诊断！

服务推荐

货号	名称	规格	价格	操作

产品推荐

货号	名称	规格	价格	操作

Recombinant Mouse PDL1(CD274) Protein (His-tag)

相关产品

注意事项