ATG-5
- 50 μL
Product Information
Description | ATG5 Mouse polyclonal |
Protein full name | ATG5 autophagy related 5 homolog (S. cerevisiae) |
Synonyms | APG5, APG5 LIKE, APG5L, Apoptosis specific protein, ASP, ATG5, Autophagy protein 5, hAPG5 |
Immunogen | Recombinant protein corresponding to Mouse ATG5OIKJ |
Isotype | IgG2a |
Purity | Affinity purification |
Subcellular location | Centrosome |
Predicted MW. | 32 kDa |
Observed MW. | 50-55/40-45 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1:1000-1:6000 | HEK-293, HeLa, Jurkat, Raji, HSC-T6, NIH/3T3 |
Background
ATG5, also named as APG5L and ASP, belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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