IL-1β
- 50 μL
Product Information
| Description | IL1 beta rabbit polyclonal |
| Protein full name | IL1 beta |
| Synonyms | Catabolin, H1, IL 1, IL 1 beta, IL-1 beta, IL1 BETA, IL1B, IL1B_HUMAN, IL1F2, Interleukin 1 beta, Interleukin-1 beta, OAF, OTTHUMP00000162031, Preinterleukin 1 beta, Pro interleukin 1 beta |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 124-223 of human IL1 beta (NP_000567.1) |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 30 kDa |
| Observed MW. | 17/30 kDa |
| Uniprot ID | P01584 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | THP-1, A-431, A-549, liver, spleen |
Background
Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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