IL-18
- 50 μL
Product Information
Description | IL18 rabbit polyclonal |
Protein full name | interleukin 18 (interferon-gamma-inducing factor) |
Synonyms | Iboctadekin, IFN gamma inducing factor, IGIF, IL 1 gamma, IL 18, IL 1g, IL18, IL1F4, Interleukin 1 gamma, Interleukin 18, Mature IL18, pre IL18, Pre-IL18 |
Immunogen | Recombinant protein corresponding to Mouse IL18 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Secreted |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB, IP | Human, Rat | 1: 1000-1: 4000 | HeLa , HaCaT , DU 145 |
Background
IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 22 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody 10663-1-AP is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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