Fibronectin
- 50 μL
Product Information
| Description | Fibronectin rabbit polyclonal |
| Protein full name | Fibronectin |
| Synonyms | CIG, Cold insoluble globulin, ED B, Fibronectin, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF |
| Immunogen | Fibronectin fusion protein Ag8004 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 263 kDa |
| Observed MW. | 250-275 kDa |
| Uniprot ID | P02751 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat, Porcine, Swine | 1: 300-1: 2000 | NIH/3T3, plasma, MDA-MB-453s |
Background
Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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