timp-1
￥0
货号：YB13495
品牌：YIKE
规格：
- 50 μL
数量：
Product Information
| Description | TIMP-1 rabbit polyclonal |
| Protein full name | TIMP metallopeptidase inhibitor 1 |
| Synonyms | CLGI, Collagenase inhibitor, EPA, EPO, HCI, Metalloproteinase inhibitor 1, TIMP, TIMP1 |
| Immunogen | Recombinant protein corresponding to Mouse TIMP-1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 23 kDa |
| Observed MW. | 21 kDa |
| Uniprot ID | P01033 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep | 1: 1000 | brain, liver |
Background
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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