timp-2
- 50 μL
Product Information
| Description | TIMP2 rabbit polyclonal |
| Protein full name | Tissue Inhibitor Of Metalloproteinase 2 |
| Synonyms | TIMP2, CSC-21K, DDC8 |
| Immunogen | Recombinant protein corresponding to Mouse TIMP2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 24 kDa |
| Observed MW. | 26 kDa |
| Uniprot ID | P16035 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 2000 | spleen, lung, brain |
Background
The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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