Anti-Cofilin Rabbit pAb
- 100 μL
Product Information
Description | Cofilin rabbit polyclonal antibody |
Protein full name | Cofilin-1 |
Synonyms | CFL1, CFL, HEL-S-15, Cofilin, Cofilin 1, 18 kDa phosphoprotein, Cofilin non musclei soform, p18 |
Immunogen | Recombinant protein corresponding to Mouse Cofilin |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Nucleus, Cell membrane, Cytoskeleton |
Uniprot ID | P23528, P45592, P18760 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:1000-1:2000 | brain, kidney, liver, lung, ovary, testis |
Background
Cofilin 1 (non-muscle; n-cofilin), also known as CFL1, is a member of the ADF/cofilin family. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. One group reports that reelin signaling leads to serine3-phosphorylation of cofilin-1, and this interaction may play a role in the reelin-related regulation of neuronal migration.
Images
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Immunohistochemistry of paraffin embedded mouse kidney using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse liver using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat kidney using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat liver using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse ovary using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using cofilin (YB11578) at dilution of 1:1000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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