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Jagged1

¥0
货号:YB13550
品牌:YIKE
规格:
  • 50 μL
数量:

Product Information


Description Jagged1 rabbit polyclonal
Protein full name Protein jagged-1
Synonyms AGS, AHD, AWS, CD339, JAG1, JAGL1, Jagged1, MGC104644, Protein jagged-1, hJ1, jagged 1 (Alagille syndrome),
Immunogen Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu1140 (intracellular region) of human Jagged1.
Isotype IgG
Purity Affinity purification
Predicted MW. 180 kDa
Observed MW. 180 kDa
Uniprot ID P78504




Applications


Applications Species Dilution Positive Tissue
WB Human,  Mouse 1: 200-1: 1000 HeLa, MCF-7




Background

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (Y2036).


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