Anti-AMPK alpha 1 Rabbit pAb
- 50 μL
Product Information
Description | AMPK alpha 1 rabbit polyclonal |
Protein full name | 5'-AMP-activated protein kinase catalytic subunit alpha-1 |
Synonyms | AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1 |
Immunogen | KLH conjugated synthetic peptide derived from human AMPK alpha 1:351-450/559 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Predicted MW. | 64 kDa |
Observed MW. | 64 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 200-1: 1000 | HepG2, HeLa |
IHC-P/IHC-F | Human, Mouse, Rat | 1: 100-1: 500 | colon carcinoma, brain |
Background
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （Y2036）.
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